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Successful Treatment in a Patient With Long-standing Myelofibrosis

Franklin Price, MD; Herbert Bell, MD

JAMA. 1985;253(19):2876-2877.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

MYELOFIBROSIS is not uncommon, but compression of the spinal cord due to extramedullary hematopoiesis in this condition is rare.

Of the 11 cases of extramedullary hematopoiesis causing spinal cord compression in the spinal epidural space that have been reported in the literature, six were associated with myelofibrosis and five with thalassemia major.^1-5 We report the 12th case, which involved the successful treatment of a woman with longstanding myelofibrosis, who underwent surgical decompression followed by radiation treatment for this condition.

Report of a Case

A 74-year-old woman was diagnosed as having myelofibrosis by the results of a bone marrow biopsy in January 1981. Initial treatment with oxymetholone and folic acid was continued until April 1983, at which time prednisone was added because of persistent hemoglobin values of about 5 g/dL. On repeated office visits thereafter, the hemoglobin values were about 10 g/dL. There was no objective evidence of blood loss. . . . [Full Text PDF of this Article]

Author Affiliations
From the Departments of Medicine (Dr Price) and Neurosurgery (Dr Bell), Huron Road Hospital, Cleveland.

Footnotes
Reprint requests to 14055 Cedar Rd, South Euclid, OH 44118 (Dr Price).

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