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A Study of Six Hundred and Eighty-Four Proved Cases

Ernest L. Wynder; Evarts A. Graham, M.D.

JAMA. 1985;253(20):2986-2994.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

General Increase.—

There is rather general agreement that the incidence of bronchiogenic carcinoma has greatly increased in the last half-century. Statistical studies at the Charity Hospital of New Orleans (Ochsner and DeBakey),¹ the St. Louis City Hospital (Wheeler)² and the Veterans Administration Hospital of Hines, Ill. (Avery)³ have revealed that at these hospitals cancer of the lung is now the most frequent visceral cancer in men.

Autopsy statistics throughout the world show a great increase in the incidence of bronchiogenic carcinoma in relation to cancer in general. Kenneway and Kenneway,⁴ in a careful statistical study of death certificates in England and Wales from 1928 to 1945, have presented undoubted evidence of a great increase in deaths from cancer of the lung. In this country statistics compiled by the American Cancer Society show a similar trend during the past two decades.⁵

Tobacco as a Possible Cause . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Department of Surgery, Washington University School of Medicine and Barnes Hospital.

Footnotes
This study has been aided by a grant from the American Cancer Society. Other phases of it will be presented in subsequent publications.

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