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Gary P. Wormser, MD

JAMA. 1985;253(23):3441-3442.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The articles by Fischl et al¹ and Burkes et al² that appear elsewhere in this issue nicely illustrate the scope of infectious and neoplastic complications found in the acquired immunodeficiency syndrome (AIDS). Just two patients were reported, but between them they had no fewer than nine different infections and two malignancies, including human T-cell lymphotropic virus (HTLV-III) infection, oral candidiasis, Pneumocystis carinii pneumonia, cytomegalovirus infection, fungal brain infection, Toxoplasma brain abscesses, tuberculosis, cysticercosis, Epstein-Barr virus infection, Kaposi's sarcoma, and non-Hodgkin's lymphoma.

Convincing evidence now exists that the cause of AIDS is a retrovirus, HTLV-III, and that this infection may be associated with a profound and progressive cellular immunodeficiency state.³ Other data also indicate the possibility of impaired humoral defenses, but in adults, so far, this has led to comparatively few clinical sequelae.⁴ Serious opportunistic infections and/or Kaposi's sarcoma dominate what appear to be the later . . . [Full Text PDF of this Article]

Author Affiliations
New York Medical College Valhalla

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