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Report of the AMA Panel on Therapeutic Plasmapheresis

Council on Scientific Affairs

JAMA. 1985;253(6):819-825.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE PROPER role of plasmapheresis as a treatment modality is gradually becoming better defined. Controlled trials are now either completed or under way for most of the common entities for which plasmapheresis has been applied. Data from these, as well as a number of uncontrolled studies, have been evaluated to assess the likelihood that plasmapheresis will be helpful in a given clinical situation, and the conclusions are presented in this report.

After Abel et al¹ coined the term plasmapheresis in 1914, widespread interest in this special form of blood-letting as a therapeutic modality had to await the development of practical equipment for performing safe and efficient plasma exchanges. The introduction of continuous- and intermittent-flow centrifuges in the 1960s, followed more recently by flat- and hollow-fiber filtration devices, simplified the procedure. Now plasmapheresis is a practical consideration in clinical situations in which pathogenic materials can be removed effectively from the . . . [Full Text PDF of this Article]

Author Affiliations
From the Council on Scientific Affairs, Division of Drugs and Technology, American Medical Association, Chicago.

Footnotes
Report J of the Council on Scientific Affairs, adopted by the House of Delegates of the American Medical Association at the Interim Meeting, December 1984.

This report is not intended to be construed or to serve as a standard of medical care. Standards of medical care are determined on the basis of all of the facts and circumstances involved in an individual case and are subject to change as scientific knowledge and technology advance and patterns of practice evolve. This report reflects the views of scientific experts and reports in the scientific literature as of December 1984.

Reprint requests to Council on Scientific Affairs, Division of Drugs and Technology, American Medical Association, 535 N Dearborn St, Chicago, IL 60610 (John C. Ballin, PhD).

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