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Daniel C. Love, MD
The Washington Hospital Center Washington, DC

JAMA. 1985;254(13):1720.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

I am writing to correct an error noted in Dr Price's¹ letter, "Anisocoria From Scopolamine Patches." Dr Price describes the case of a 25-year-old woman who developed lethargy, diarrhea, and a fixed and dilated pupil associated with a scopolamine patch prescribed prior to a trip on a yacht. Presumably, she inadvertently transferred scopolamine to her eye from touching or manipulating her patch. In his discussion of this case, however, Dr Price states that scopolamine contamination can be confirmed by "prompt and extensive" constriction of the pupil after instillation of 0.5% to 1.0% pilocarpine hydrochloride in the affected eye. The correct response is that failure of a dilated pupil to constrict to 0.5% to 1.0% pilocarpine is diagnostic of chemical blockade of the iris sphincter in the absence of a history of traumatic iridoplegia, acute angle closure glaucoma, or previous iris disease that would make the iris . . . [Full Text PDF of this Article]

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