To the Editor.—
Takayasu's arteritis is recognized as an arteritis that may involve the aorta and its branches. Although the etiology of this disease is unknown, there is speculation that an autoimmune mechanism is responsible.1 We report a case of this disease in a 4-year-old girl in whom Coombs' antibodies and rheumatoid factors were detected. The appearance of these autoantibodies suggests that an autoimmunologic mechanism is in operation.
Report of a Case.—
A 4-year-old girl was admitted to our hospital because of fever. Three months before admission she had a high fever for a month; blood studies revealed leukocytosis and an elevated sedimentation rate. Seven days before admission the fever recurred and persisted. Treatment was not started.
At the time of physical examination, bilateral radial pulses were absent. There was a systolic ejection murmur maximal at the second left intercostal space, and systolic bruits over the right and left
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