This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (6)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Timothy C. Fagan, MD; David G. Johnson, MD; David S. Grosso, PhD

JAMA. 1985;254(22):3217.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

METRONIDAZOLE is usually prescribed for therapeutic courses of one to ten days, but in rare instances it may be administered for longer periods. Two such circumstances involve treatment of recurrent antibioticinduced colitis and treatment of inflammation in a Kock pouch (an internal reservoir and nipple valve created from distal ileum in patients undergoing total colectomy).¹ This inflammation of the pouch is characterized clinically by profuse, watery diarrhea and occasionally by bleeding and incontinence. The symptoms respond to antibiotics, making a bacterial cause seem most likely. Metronidazole is the most effective drug for this condition, but sometimes other antibiotics are effective.¹

Report of a Case

A 36-year-old man with ulcerative colitis underwent total colectomy and creation of a Kock pouch in May 1983. Recurrent episodes of pouch inflammation, characterized by profuse watery diarrhea and mild right lower-quadrant aching, responded transiently to short courses (five to ten days) of either . . . [Full Text PDF of this Article]

Author Affiliations
From the Departments of Internal Medicine and Pharmacology (Dr Fagan and Johnson) and Obstetrics and Gynecology (Dr Grosso), University of Arizona College of Medicine, Tucson.

Footnotes
Reprint requests to General Medicine Section, Arizona Health Sciences Center, 1501 N Campbell Ave, Tucson, AZ 85724 (Dr Fagan).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?