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Harry W. Daniell, MD
Redding, Calif

JAMA. 1985;254(3):358.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The recent report in THE JOURNAL by Daling et al¹ plus the six case reports they cite^2,3 and two others reported by Frederick et al⁴ apparently identify male homosexuality as the first recognized risk factor for epidermoid carcinomas of the anus. Both the physical trauma of anal sex and the potential presence of sexually transmitted infections including herpes have been suggested as factors possibly contributing to this association. The potential for a similar association among women, who develop these tumors more frequently than do men, is suggested by the report of Bolling⁵ in which the frequency with which an urban population of women participated habitually in anal sex was much higher than the reported frequency of male homosexuality.

Since little else is known about the etiology of these tumors, another observation suggesting an additional risk factor should be of interest. During a review . . . [Full Text PDF of this Article]

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