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Alan L. Bisno, MD

JAMA. 1985;254(4):538-541.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN THIS week's issue, the editors of JAMA have republished an article that stands clearly as a landmark in modern medical history. The article, which first appeared in THE JOURNAL 35 years ago, presents convincing evidence that acute rheumatic fever may be prevented by penicillin therapy for the antecedent streptococcal throat infection. This study and a succeeding one on the same topic published the next year¹ emerged from the famous Streptococcal Disease Laboratory, which functioned at the Fort Warren, Wyo, air force technical training base in the years shortly after the end of World War II. The laboratory, under the leadership of the late Dr Charles H. Rammelkamp, Jr, included among its ranks a number of young investigators destined to make indelible contributions to the field of infectious diseases. Numbered among these were Dr Floyd W. Denny, the senior author of the 1950 JAMA article, the late Dr Lewis W. . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, Division of Infectious Diseases, University of Tennessee Center for the Health Sciences, Memphis.

Footnotes
Reprint requests to Department of Medicine, Division of Infectious Diseases, University of Tennessee Center for the Health Sciences, 956 Court Ave, Room H308, Memphis, TN 38163 (Dr Bisno).

A commentary on Denny FW, Wannamaker LW, Brink WR, et al: Prevention of rheumatic fever: Treatment of the preceding streptococcic infection. JAMA 1950;143:151-153.

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