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Mitral Valve ProlapseAn Update
Robert M. Jeresaty, MD
JAMA. 1985;254(6):793-795.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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MITRAL valve prolapse (MVP), defined as echocardiographic, angiographic, and pathological protrusion of the mitral leaflets into the left atrium during systole, may affect about 5% of the population and was first widely recognized in the mid-1960s.1-3 It is frequently associated with a click and/or murmur. A syndrome consisting of nonspecific symptoms, electrocardiographic abnormalities, and arrhythmias has been recognized by many investigators.1-3 Although doubt has recently been expressed about the existence of this syndrome,4-6 the complications of MVP,2,7-10 albeit rare, earn for it an important place in modern cardiology and may represent its "raison d'être."
Pathology and Etiology
Because of the generally benign course of MVP, its underlying pathology has been well documented only in advanced forms that are associated with severe mitral insufficiency and have been termed the "floppy mitral valve."7,8 Of great interest has been the demonstration of similar pathological changes in 26 patients
. . . [Full Text PDF of this Article]
Author Affiliations
From the Section of Cardiology, Department of Medicine, St Francis Hospital and Medical Center, Hartford, Conn; and the Division of Cardiology, Department of Medicine, University of Connecticut School of Medicine, Farmington.
Footnotes
This article is one of a series sponsored by the American Heart Association.
Reprint requests to Section of Cardiology, St Francis Hospital and Medical Center, 1140 Woodland St, Hartford, CT 06 105 (Dr Jeresaty).
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