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Peter P. Morgan, MD, DPH
Canadian Medical Association Journal Ottawa

JAMA. 1985;254(8):1033.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.—

Even if the treatments being compared are equivalent, randomized allocation must be substituted for any preference the physician might have for a particular treatment in a given patient: hence, "judgment is set aside." The word "substandard" may be a little strong; however, if one of the treatments in the trial emerges as distinctly superior to the others, patients having received the latter have—inadvertently—been given an inferior treatment during the trial.

I assume that physicians explain these two fundamental concepts to patients whom they are encouraging to participate in a clinical trial. . . . [Full Text PDF of this Article]

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