To the Editor.—
A number of articles in a recent issue of THE JOURNAL concerned heterosexual transmission of human T-cell lymphotropic virus type III (HTLV-III).1-3
While HTLV-III transmission from semen donor to semen recipient (either male to female or male to male) is well documented, the reverse route of transmission (female to male) is not. The evidence, to date, to support such transmission remains entirely based on untested epidemiologic observations.
Dr Redfield and his colleagues are to be congratulated for their continued efforts to provide "evidence for both male-to-female and female-to-male transmission of infection and disease."1 I am not convinced, however, that they have yet completely succeeded in their goal.
They report on ten men with HTLV-III-associated diseases who denied traditional risk factors. Eight of the ten reported multiple sexual contacts (>50 in the past five years), including, in most, a history of sex with prostitutes. They report, in
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