 |
|
Failure of Recommended Treatment for Secondary Syphilis
David M. Markovitz, MD;
Karl R. Beutner, MD, PhD;
Russell P. Maggio, MD;
Richard C. Reichman, MD
JAMA. 1986;255(13):1767-1768.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
THE CENTERS for Disease Control (CDC) currently recommends that early syphilis (primary, secondary, and latent syphilis of less than a year's duration) be treated with 2.4 million units of penicillin G benzathine administered intramuscularly (IM) at a single session.1 This treatment schedule has been found to have a clinical and/or serological failure rate ranging from less than 1% to 3%.2-4 Other regimens have been reported to be more effective,5,6 and controversy exists regarding optimal antibiotic treatment of early disease. We recently witnessed a dramatic relapse of secondary syphilis that occurred five months after the patient had been treated according to current CDC guidelines.
Report of a Case
A 21-year-old white male homosexual was admitted to Strong Memorial Hospital of the University of Rochester, NY, in July 1984, with a generalized rash, left leg weakness, and a positive rapid plasma reagin test (RPR). He had been sexually active
. . . [Full Text PDF of this Article]
Author Affiliations
From the Infectious Diseases Unit (Drs Markovitz and Reichman) and the Dermatology Unit (Dr Beutner), Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY.
Footnotes
Reprint requests to Infectious Diseases Unit, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, PO Box MED, Rochester, NY 14642 (Dr Reichman).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
