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Cerebral Infarction, Lupus Anticoagulant, and Habitual Abortion
Jeffrey S. Greenspoon, MD
Women's Hospital Los Angeles
JAMA. 1986;255(16):2164.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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To the Editor.—
The report of Drs Wiebers and Whisnant1 indicates that cerebral infarction during pregnancy is indeed a rare event. When it does occur, a thorough evaluation is justified because a treatable cause is often found.2,3 The single case of cerebral infarction identified in the Rochester (Minn) study was that of a 28-year-old woman whose six pregnancies ended in spontaneous abortion.
Recently, obstetricians have become aware of the association between the lupus anticoagulant and fetal wastage.4-6 Patients with the lupus anticoagulant have been reported to experience a higher frequency of both arterial and venous thrombotic events.7,8 A history of pregnancy loss and thrombotic events is typical for patients with the lupus anticoagulant. When this unusual combination of clinical misfortunes occurs, a test for the lupus anticoagulant should be included in the evaluation. Triplett et al9 have shown that the platelet neutralization procedure is more
. . . [Full Text PDF of this Article]
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