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Robert M. Michaels, MD; Rodney F. Hochman, MD
Guthrie Clinic Ltd Sayre, Pa

JAMA. 1986;255(18):2444.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The article by McCarty et al¹ described ten elderly patients with an acute-onset seronegative symmetric synovitis associated with pitting edema of the hands and feet, which completely remitted over several months. The authors believe that these cases were representative of a distinctive syndrome and chose to call it "remitting seronegative symmetrical synovitis with pitting edema" (RS₃PE syndrome). In their discussion, the authors postulate that an infectious agent might trigger this syndrome in a genetically programmed host. We have recently seen a patient identical to that described by McCarty et al, in whom an infectious agent known to cause a reactive arthritis, Campylobacter jejuni, was isolated by routine stool culture.²

Report of a Case.—

On Feb 4, 1985, a 62-year-old man began experiencing a sore throat, nausea, vomiting, an episode of diarrhea, and fever. On the morning of Feb 10, 1985, he awoke . . . [Full Text PDF of this Article]

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