
The Management of Hyperlipoproteinemia
Robert Gaudet, MD, PhD
University of Maryland School of Medicine Baltimore
JAMA. 1986;255(21):2895.
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To the Editors.—
The article by Hoeg et al1 provided valuable guidelines for the evaluation and treatment of persons with elevated levels of serum lipids. Individuals with serum cholesterol in the upper tenth percentile for their age and sex are considered to be at high risk for atherosclerotic sequelae. Those with levels in the 75th to 90th percentiles are considered to be at moderate risk. The authors advocate screening virtually all persons for elevated cholesterol levels using automated analyzers. These devices output the results of chemical panels or single cholesterol values on preprinted forms. In many laboratories the results are compared with a previously determined normal range. Chemistry values above the normal range are flagged (usually with "H," "+," or "*") or set aside in separate columns to indicate abnormality. Normal ranges are set according to manufacturers' specifications based on population studies or from the laboratory's previous experience. Although techniques used
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