To the Editor.—
In the July 12th issue of JAMA, Drs Williams and Jones1 conclude that the capillary-fragility tourniquet test is "of no value in screening for diabetic retinopathy." The conclusion is based on the following data:
The conclusion seems entirely warranted because the sensitivity of a positive test in patients with retinopathy is 54% (27/50)—a value too low to make the test useful for general screening purposes. The relatively low specificity (65% =13/20 and 80% =16/20) in the two control groups is also discouraging because the test would lead to many false-positive results. On the other hand, when the test was "strongly positive," the authors' data show the following:
If accurate and reproducible in other groups of patients, these data suggest that a strongly positive tourniquet test is excellent, not in screening for retinopathy, but in confirming it. The concept is analogous to doing a bronchoscopic biopsy in
. . . [Full Text PDF of this Article]