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Jesse B. Hall, MD

JAMA. 1986;255(7):930-933.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SLIGHTLY more than 100 years following the publication of the Pick-wick Papers, wherein Charles Dickens described the hypersomnolent and obese character Joe, the term pickwickian syndrome was applied to a group of patients exhibiting obesity, hypersomnolence, hypoventilation, and erythrocytosis.¹ Since this descriptive report, a large amount of information regarding the clinical spectrum, pathophysiology, and treatment of various forms of sleep-induced breathing disorders has been generated,² requiring increased clinical awareness of methods of diagnosis and treatment. Sleep-induced breathing disorders include the following: sleep apnea syndromes, such as central, obstructive, and mixed apnea; primary alveolar hypoventilation; periodic or irregular breathing patterns; and nocturnal hypoxemia in chronic obstructive pulmonary disease (COPD) or neuromuscular disorders (NMD).

Apneas are defined as the complete cessation of ventilation and may be analyzed by polysomnography³—the simultaneous recording during sleep of an electroencephalogram (to characterize sleep stage and pattern), measures of airflow (by means of . . . [Full Text PDF of this Article]

Author Affiliations
From the Medical Intensive Care Unit, Section of Pulmonary and Critical Care Medicine, Department of Medicine, the University of Chicago.

Footnotes
Reprint requests to the Medical Intensive Care Unit, Section of Pulmonary and Critical Care Medicine, Department of Medicine, the University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637 (Dr Hall).

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