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The Rewards of Clinical Trials

Howard M. Spiro, MD

JAMA. 1986;255(9):1174-1175.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SOME years ago emphasis on informed consent made me realize that I could get most of my patients to participate in almost any kind of clinical study. They would swallow new drugs, receive infusions of calcium or glucagon, or even embrace esophageal or rectal catheters because they had faith in my goodwill or, I now fear, because they wanted to please me. Differences between patients and subjects were not always explicit in earlier times, and I am sure that other academic physicians also had the idea that we had the implicit right to carry out experimental observations on patients without telling them what we were doing. Certainly there was an unexpressed agreement that charity patients, beneficiaries of endowed "free" beds, were under some obligation to repay the beneficences bestowed on them by participating in our experiments. We gave them our minds and they gave us their bodies in a "civic . . . [Full Text PDF of this Article]

Author Affiliations
From the Program for Humanities in Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.

Footnotes
Reprint requests to Gastroenterology Unit, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar St, PO Box 3333, New Haven, CT 06510 (Dr Spiro).

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