This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

John R. Hughes, MD
University of Vermont Burlington

Dorothy Hatsukami, PhD
Kelli Skoog University of Minnesota Minneapolis

JAMA. 1986;256(23):3215.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.—

Drs West and Russell believe that any nicotine dependence in our subjects was present prior to their use of nicotine gum; ie, nicotine gum maintained an old dependence rather than caused a new one. We agree that this is possible, and that was the reason for using the phrase "develop (or maintain)" in the article. We disagree that it can be said to be true for all of our subjects since not all smokers are physically dependent on nicotine (ie, have withdrawal upon cessation of smoking that is relieved by nicotine).^1,2

Drs West and Russell imply that the generalizability of our results is limited because we used a "highly selected" sample. In fact, unlike their study, which included only smokers who had used the gum for at least 12 months, five of our eight subjects had used the gum for less than six months and three had . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?