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Use of Synchronized Capacitor Discharge

Bernard Lown, M.D.; Raghavan Amarasingham, M.B., B.S.; Jose Neuman, M.D.

JAMA. 1986;256(5):621-627.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE ECTOPIC TACHYCARDIAS are currently treated by either vagal stimulation or drugs. The 3 most effective drugs are quinidine, procainamide hydrochloride, and the digitalis glycosides. When the ectopic mechanism drives the ventricles at rates above 160 per minute, cardiac output falls and coronary blood flow is compromised. This is most likely to occur with ventricular tachycardia which constitutes a serious cardiac emergency requiring immediate treatment. Frequently, however, the arrhythmia cannot be terminated promptly. Reversion with drugs generally involves a time-consuming biologic titration. Since it is impossible in any one patient to predict either the effective or the toxic dose, small increments of antiarrhythmic drugs are given at frequent intervals until a therapeutic end point is reached. The interval between doses is determined by the gravity of the patient's illness as well as by the rapidity of action of the particular agent. It may thus take minutes, days, or even weeks . . . [Full Text PDF of this Article]

Author Affiliations
Boston

From the Department of Nutrition, Harvard School of Public Health, and the Medical Clinics, Peter Bent Brigham Hospital.

Footnotes
Presented in part before the 54th Annual Meeting of the Society for Clinical Investigation, April 30, 1962.

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