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HTLV-III Antibodies in Drug-Addicted Prostitutes Used by US Soldiers in Italy
Umberto Tirelli, MD;
Emanuela Vaccher, MD;
Roberto Sorio, MD;
Antonino Carbone, MD;
Silvio Monfardini, MD
Centro di Riferimento Oncologico Aviano, Italy
JAMA. 1986;256(6):711-712.
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To the Editor.—
The controversial issue of the human T-cell lymphotropic virus type III (HTLV-III) infection rate among US soldiers in Berlin and its relationship with use of prostitutes,1,2 in particular intravenous drug abusers, prompted us to report our data from Italy. To study the relationship between HTLV-III infection and the development of malignant lymphoma, 315 intravenous drug abusers seen in five centers for drug addicts from three provinces (Pordenone, Udine, and Gorizia) of Friuli Venezia Giulia, a region of 1.5 million inhabitants close to the borders of Austria and Yugoslavia, were clinically examined. They were also given laboratory tests including an HTLV-III antibody test (enzyme-linked immunosorbent assay) and T4/T8 ratios and completed a questionnaire on their drug abuse and sexual behavior.
Human T-cell lymphotropic virus type III antibodies were detected in 86 (27% ) of the overall population, and 65 intravenous drug abusers (21%) were affected by persistent generalized
. . . [Full Text PDF of this Article]
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