This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (17)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Jorge Fernández de Castro, MD; José Luis Valdespino Gómez, MD; José Luis Díaz Ortega, MD; Ma. Luisa Zárate Aquino, MD
Secretaria de Salud; Secretaria de Salud;Instituto de Salubridad Mexico City

JAMA. 1986;256(6):714.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Dr Albert Sabin and one of us (J.F.D.)^1,2 recently reported seroconversion in infants administered measles vaccine of human diploid cells (HDCs) that contained the Iki (Edmonston-Zagreb) strain and 1% human albumin, or chick embryo fibroblast (CEF) vaccine that contained the Edmonston-Schwartz strain by cutaneous or aerosol routes. In that study, we used enzyme-linked immunosorbent assay and plaque neutralization tests to demonstrate seroconversion. In this letter we report a further study in which antibody was measured using the more standard hemagglutination inhibition. This double-blind study was carried out in children aged 6 to 8 months residing in two poor urban areas of Mexico City between October 1983 and April 1984.

Report of a Case.—

One hundred seventy-two children received HDC vaccine manufactured in Mexico: 117 via aerosol (titer of virus, 10^5.2 50% tissue culture infective dose per milliliter), and 55 by injection (titer of virus, 10 . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?