This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (6)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Gary R. Gibson, MD; Gary A. Schnur, MD

JAMA. 1986;256(8):1035.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ELEVATION of creatine kinase (CK) isoenzymes in patients with malignancies has been reported. The isoenzyme BB is commonly present in stage D prostate cancer but has also been reported in lung cancer of all histological types. This ectopic CK-BB may migrate to atypical positions on gel electrophoresis, depending on whether it forms complexes with immunoglobulins or other macromolecules. By contrast, the MB isoenzyme is rarely produced ectopically from carcinoma.¹ The patient described herein had a metastatic adenocarcinoma and a CK electrophoretic pattern on cellulose acetate that showed a normal MM peak with a larger peak anodal to the MM peak, in the position normally occupied by the CK-MB isoenzyme.

Report of a Case

A 66-year-old man was admitted to the Trumbull Memorial hospital with a two-day history of progressive dyspnea and pedal edema. Five months earlier, he had presented with pain in the right hip, weight loss, and a . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, Trumbull Memorial Hospital. Warren, Ohio.

Footnotes
Reprint requests to 1651 E Market St, Warren, OH 44483 (Dr Gibson).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?