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Lawrence D. Kaplan, MD; Constance B. Wofsy, MD; Paul A. Volberding, MD

JAMA. 1987;257(10):1367-1374.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PATIENTS with the acquired immunodeficiency syndrome (AIDS) suffer from a variety of opportunistic infections and malignancies. There is, as of yet, no known cure for this disease.

Early in the course of the AIDS epidemic, therapy was directed only toward the management of manifestations of the disease (opportunistic infections and malignancies). As the immunologic abnormalities associated with AIDS became more clearly defined and with the discovery of the human immunodeficiency virus (HIV), treatment of the underlying immunodeficiency disorder with immunomodulators or antiviral agents became a possibility. This review will focus both on treatment of the disease manifestations and on more recent investigations into the use of immunomodulators and antiviral agents. The role of supportive care, which is important in the treatment of patients with this disease, has been discussed elsewhere.¹

TREATMENT OF CLINICAL MANIFESTATIONS OF AIDS

Opportunistic Infections

The therapeutic approach to AIDS patients with . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Medicine, San Francisco General Hospital, and University of California, San Francisco.

Footnotes
Reprint requests to San Francisco General Hospital, 995 Potrero Ave, Ward 84, San Francisco, CA 94110 (Dr Kaplan).

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