To the Editor.—
I am chairman of our hospital's bioethics committee and a past chairman of our hospital and medical school's institutional review board (IRB) (the committee that oversees research on human subjects). I am therefore interested in current research practices related to human subjects and in the practice of scientific journals that report research performed on humans.
Three articles in the May 15, 1987, issue of JAMA raise questions in my mind about the adequacy of review by IRBs. In two of the articles I do not find mention of IRB review, while in the third article "no consent" was deemed necessary by the IRB.
Research described by Bartholomew et al1 was performed outside the United States, where IRB standards may be different from those inside the country. The research was a collaborative effort of foreign organizations and the US National Cancer Institute. It used blood specimens that
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