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Charles H. Kirkpatrick, MD

JAMA. 1987;258(20):2993-3000.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

TRANSPLANTATION of tissues and organs is an artificial biologic event, but it has provided a means for temporary or long-term treatment for failure of a variety of organs. Corneal transplantation has restored sight to thousands of persons,¹ and skin grafts are regularly used to cover injured tissues in burn patients. Since the 1960s, kidney transplantation has prolonged the healthy and productive lives of many persons with chronic renal failure.² Transplantation of bone marrow is widely used for treatment of aplastic anemia^3-5 and is beneficial for some patients with malignant diseases such as leukemia^6-9 or immune deficiency syndromes.¹⁰ Bone marrow transplantation is also being evaluated as a method for correction of certain genetically determined diseases.¹¹ During recent years, transplantation of the heart^12-14 and liver^15,16 has become common, and progress is being made toward successful transplantation of the lung,¹⁷ pancreas,¹⁸ and other organs. . . . [Full Text PDF of this Article]

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