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Update 1987

John Speer Schroeder, MD; Sharon Hunt, MD

JAMA. 1987;258(21):3142-3145.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

JANUARY 1988 will mark the 20th anniversary of the performance of the first human cardiac transplant in the United States by Dr Norman Shumway, following nearly a decade of laboratory work developing and validating the technique involved. During these 20 years cardiac transplantation has evolved from what was initially considered a radical and experimental form of therapy to one that is currently viewed in most of the world as a valid form of advanced therapy for end-stage heart disease. The initial flurry of enthusiasm for this newsworthy procedure in 1968 quickly subsided when it became evident that the complexities of postoperative treatment went far beyond those of ordinary cardiac surgery and, although the surgical mortality rate was low, patient survival rates were initially measured in terms of days or months. The introduction during the ensuing years of a variety of improvements in immunosuppressive monitoring and treatment led to improving survival . . . [Full Text PDF of this Article]

Author Affiliations
From the Cardiology Division, Department of Medicine, Stanford University School of Medicine, Stanford, Calif.

Footnotes
This article is one of a series sponsored by the American Heart Association.

Reprint requests to the Stanford University School of Medicine, Division of Cardiology CV269, Stanford, CA 94305 (Dr Schroeder).

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