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M. Bortolotti, MD; G. Trisolino, MD; L. Barbara, MD
University of Bologna Italy

JAMA. 1987;258(24):3516.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Anticholinergics are commonly used in the treatment of biliary and renal colic because of their spasmolytic effect, but when they fail to relieve pain or produce undesirable side effects the only alternatives are morphine and related narcotic-analgesics. However, some calcium antagonists, such as nifedipine, show spasmolytic activity on smooth-muscle cells.¹ This action is utilized in the treatment of cardiovascular diseases where there is arteriolar spasm² and in the treatment of some diseases of the gut where spasm is pathogenetically important.³

Study.—

We carried out a preliminary study on the spasmolytic effect of nifedipine in biliary and renal colic when compared with one of the most commonly used anticholinergics, scopolamine butylbromide (Buscopan). The study was carried out randomly on a total of 32 patients, 16 with biliary colic and 16 with renal colic, admitted consecutively to the University Hospital of Bologna. Patients who had received . . . [Full Text PDF of this Article]

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