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Hematologic Data on Healthy Very Old People
Edzard Ernst, MD;
Arpad Matrai, MD
University of Munich West Germany
JAMA. 1987;258(6):781-782.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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To the Editor.—
Zauber and Zauber1 conclude from their investigation of old, apparently healthy people that hematologic data are essentially unaffected by age. However, the population studied was small, several inclusion criteria seem somewhat vague, and significant differences were seen between old and young men, mainly in regard to hemoglobin-dependent variables. There thus seems to be a contradiction between their data and their conclusion.
Study.—
In an epidemiologic study,2 we recently tested a random sample of the population (n = 4022). Using strict criteria (no signs of chronic disease; no smoking; no medications; blood pressure <160/95 mm Hg; cholesterol level <6.70 mmol/L [260 mg/dL]; urea level <400 mmol/L [1120 mg/dL] in men and <340 mmol/L [952 mg/dL] in women; body mass index <30 kg/m2; and a normal resting electrocardiogram), 567 persons were defined as healthy. Among other factors, we measured hemoglobin level and plasma viscosity. These data are
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