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Finding the High-Risk Patient With Coronary Artery Disease
Melvin D. Cheitlin, MD
JAMA. 1988;259(15):2271-2277.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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OVER the years, many clinical studies have been reported that relate clinical, angiographic, and hemodynamic variables to prognosis in the patient with coronary artery disease.1-4 The complications of coronary disease considered to constitute "bad" prognosis vary and include congestive heart failure, myocardial infarction, and death, as well as reversible end points such as the development of life-threatening arrhythmias, unstable angina, and angina requiring bypass surgery. These studies have been both retrospective and prospective and have identifed a number of clinical and laboratory variables related to the selected prognostic end points, first in a univariate and then in a multivariate analysis. This allows subdivision of the patients into high- and low-risk groups, relating risk to the morbidity and mortality achievable by medical treatment of patients with coronary artery disease.
Because coronary atherosclerosis progresses with time, whatever risk stratification is done should be periodically repeated. The interval depends on whether there
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Medicine, University of California School of Medicine, and Cardiology Division, San Francisco General Hospital, San Francisco.
Footnotes
This article is one of a series sponsored by the American Heart Association.
Reprint requests to Department of Medicine, San Francisco General Hospital, Room 5G1, 1001 Potrero Ave, San Francisco, CA 94110 (Dr Cheitlin).
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