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Eiji Kato, MD; Shizuo Shindo, MD; Yoshiharu Eto, MD; Nobuo Hashimoto, MD; Masashi Yamamoto, MD; Yasutaka Sakata, MD; Yasuhiko Hiyoshi, MD
St Mary's Hospital Kurume, Japan

JAMA. 1988;259(22):3269-3271.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—We report herein a case of aseptic meningitis probably caused by administration of immune globulin, which resulted in headache, vomiting, and fever.

Report of a Case.

—A 2-year-old girl was admitted to the hospital on April 29, 1986, for treatment of acute idiopathic thrombocytopenic purpura. She was treated with 20 mg/d of corticosteroids for four weeks, but no rise in platelet count occurred. After three more days of this therapy, she was given 100 mg/d of hydrocortisone intravenously, followed by 0.4 g/kg/d of immune globulin prepared with polyethylene glycol for five days. Seven days after this therapy, she experienced headache and vomiting. Her temperature rose to 38.5°C and neck stiffness developed. The white blood cell count was 15.6 x 10⁹/L (15 600/mm³), with 0.04 (4%) band forms, 0.64 (64%) segmented neutrophils, 0.27 (27%) lymphocytes, and no eosinophils. Tests for C-reactive protein were negative. The . . . [Full Text PDF of this Article]

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