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Meir Stampfer, MD; Graham Colditz, MD
Brigham and Women's Hospital Harvard Medical School Boston

JAMA. 1988;259(4):518.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—We were surprised to see our recent study¹ badly misrepresented in the title and lead-in of the MEDICAL NEWS & PERSPECTIVES story entitled "Will Epidemiology Answer the Estrogen Question?"² The story appeared to suggest that this study questioned the cardiovascular protection from postmenopausal estrogen therapy. On the contrary, that study confirmed the marked protection conferred by replacement hormones among women after bilateral oophorectomy. It did not directly address the issue for women with natural menopause, but an earlier report from the Nurses' Health Study³ showed a substantial protective effect among those women as well. The main focus of the recent work was to show that, contrary to popular belief, cessation of menses is not accompanied by an abrupt increase in risk of heart disease. This finding in no way suggests that postmenopausal estrogen therapy would not have a benefit. As we pointed out earlier, . . . [Full Text PDF of this Article]

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