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Paul D. Cleary, PhD; Michael J. Barry, MD; Kenneth H. Mayer, MD; Allan M. Brandt, PhD; Larry Gostin, JD; Harvey V. Fineberg, MD, PhD
Harvard Medical School Boston

JAMA. 1988;259(7):1014.

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In Reply.

— The comments by Mr Daniels and by Drs Allain, Bridgeman, Cummins, Fahs, Schechter, and Franklin primarily concern specific assumptions on which our analyses are based and so we would like to clarify our rationale for making those assumptions.

There have been numerous studies that indicate that certain groups have higher prevalences of HIV infection than do blood donors. As stated in our original article, we used data from blood donors instead of other populations because we think they are most similar, in terms of risk factors, to persons who are about to be married. Army recruits are demographically different from the premarital population and are more likely to be sexually active, homosexual men and drug abusers.^1,2 The study of infection in Massachusetts infants includes all infants born and thus overrepresents women with higher parity and includes unmarried mothers. Only 63% of the first births in 1980 . . . [Full Text PDF of this Article]

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