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Etiology, Diagnosis, and Treatment

Barbara Linder, MD, PhD; Fernando Cassorla, MD

JAMA. 1988;260(21):3171-3175.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SELECTED CASE

THE PATIENT is a 12 3/12-year-old Colombian boy with growth hormone deficiency. He was the full-term product of twin gestation and was born by repeated cesarean section, without complication. His birth weight was 2.5 kg and his twin sister's was 2.3 kg. Early growth and development were normal; however, by the end of the first year of life, the patient's growth was lagging behind that of his twin. Workup in Colombia reportedly revealed a parasitic infection. After appropriate treatment, growth velocity increased transiently. By the age of 2 years, however, growth velocity had again declined and by the age of 3 years, the patient was reportedly 10 to 12 cm shorter than his twin sister. The mother is 167 cm tall, the father is 190 cm, and a 14-year-old sister was 172 cm at the time.

This child was first seen at the National Institutes of Health, Bethesda, . . . [Full Text PDF of this Article]

Author Affiliations
From the Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, Md.

Footnotes
Presented Feb 3, 1988, at Clinical Center Grand Rounds, National Institutes of Health.

Reprint requests to the Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892 (Dr Linder).

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