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Hadyn T. Williams, MD
Veterans Administration Medical Center Hospital of the University of Pennsylvania Philadelphia

JAMA. 1988;260(5):635.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Dr Cheitlin¹ deserves our thanks and commendations for his recent excellent review of risk stratification in patients with coronary artery disease. His proposed diagnostic algorithm is straightforward and appears very practical.

However, certain aspects of Table 1 of his article, which compares the various techniques available for risk stratification, need further clarification. Positron-emitting isotopes are usually obtained from a cyclotron (charged-particle accelerator), not from a breeder reactor as stated in the table. Breeder reactors, which utilize fast neutrons to produce large amounts of electricity from uranium with high efficiency, have not been as widely used as the more familiar thermal or slow-neutron nuclear reactors. This is due to justified concerns over safety problems with the more unstable breeder reactors. Cyclotrons have been safely employed in the extensive production of radioisotopes for decades, and carry none of the meltdown risks of breeder reactors.

Placing radionuclide wall motion . . . [Full Text PDF of this Article]

Footnotes
Edited by Drummond Rennie, MD, Deputy Editor (West); Jody W. Zylke, MD, Contributing Editor; Sharon Iverson, Assistant Editor.

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