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Benign Familial Hematuria
Israel Zelikovic, MD;
F. Bruder Stapleton, MD;
Russell W. Chesney, MD
University of Tennessee College of Medicine Memphis
JAMA. 1988;260(9):1241-1242.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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To the Editor.—
We read with interest the article by Blumenthal et al1 concerning the importance of examining the urine sediment of patients and family members in establishing the diagnosis of benign familial hematuria. We concur with their notion of reducing the number of painful and costly urologic and radiological procedures in patients with hematuria but believe that the authors have failed to evaluate and discuss an important cause of hematuria, at least in children. This cause is idiopathic hypercalciuria, an entity with a familial occurrence pattern that is being recognized as a major cause of gross and microscopic hematuria in children.2,3
Hypercalciuria, defined as urinary calcium excretion of more than 4 mg/kg of body weight every 24 hours or as a calcium/creatinine ratio of more than 0.21 (mg/mg) in a urine sample collected over a two-hour period,3 was prospectively found in 78 (36%) of 215 children
. . . [Full Text PDF of this Article]
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