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Daniel Tripodi, PhD
THERAKOS West Chester, Pa

JAMA. 1989;261(13):1882.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The report by Drs Weinstock and Horm¹ of a significant increase in the incidence of mycosis fungoides over a study period from 1973 through 1984 is of considerable interest. As the authors point out, the etiology of this disease is obscure, but the recent observation of an association between infection by the human T-cell lymphotropic virus type V and disease² is worth noting. These findings also support the view that a human T-cell lymphotropic virus may be a factor in the etiology.

Edelson³ described the relationship between mycosis fungoides and the Sézary syndrome as variants of a T-cell-mediated disease—cutaneous T-cell lymphoma. While Drs Weinstock and Horm¹ referred to the poor response to conventional therapy, a new form of therapy named photopheresis (the equipment for which is manufactured by Therakos) has been introduced for the treatment of cutaneous T-cell lymphoma. As originally reported by . . . [Full Text PDF of this Article]

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