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Ronald V. Loge, MD
Dillon, Mont

JAMA. 1989;261(14):2063-2064.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor. —

In a letter to the editor by Dr Lettau¹ and the reply by Drs Gerding and Gebhard,² it was suggested that oral fluoroquinolones may be a therapeutic alternative in the treatment of Clostridium difficile diarrhea. This suggestion was made despite the acknowledgment that ciprofloxacin has relatively limited in vitro activity against C difficile. However, one might anticipate that the potent fluoroquinolones would join the great number of broad-spectrum antibiotics implicated in antibiotic-associated C difficile diarrhea. The following case shows that this is so.

Report of a Case.—

A 61-year-old woman with diabetes presented with acute paronychia as a result of an ingrown toenail. The nail spicule was removed and she was given ciprofloxacin (500 mg orally twice daily for 7 days). After 1 week she developed diarrhea, with mushy frequent stools. The diarrhea persisted for 2 weeks, at which point a surgeon performed a . . . [Full Text PDF of this Article]

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