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William S. Pierce, MD

JAMA. 1989;261(19):2827-2829.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A continued refinement of techniques, careful analyses of treatment options, and long-term follow-up of patients characterize the recent progress in cardiothoracic surgery.

The survival rates of patients with lung or esophageal cancer continue to be most disappointing. Many patients have nonresectable disease when first seen. The principles of safe resection were established decades ago. However, distant metastasis or local extension of disease often results in death of the patient. Recently, Einhorn¹ critically reviewed a series of studies that evaluated the role of preoperative adjuvant chemotherapy or radiotherapy in patients with stage III non-small-cell lung cancer (advanced local disease but without distant metastasis). Pending the results of further clinical trials, Einhorn recommends resection for cure when possible and radiotherapy where curative resection is not possible. The values of preoperative chemotherapy or radiotherapy remain unproved in patients with these common lung tumors. . . . [Full Text PDF of this Article]

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