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Arthur Ulene, MD
Feeling Fine Programs Inc Los Angeles, Calif

JAMA. 1989;261(22):3241.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply. —

The belief by Dr Stare that a high level of blood cholesterol is of minor importance as a risk factor in the development of coronary heart disease is an opinion that is not shared by the majority of experts in this subject area. A total blood cholesterol level of 6.21 mmol/L more than doubles the risk of death due to coronary heart disease compared with a level of 5.17 mmol/L; a level of 7.76 mmol/L quadruples the risk.^1,2 There also is substantial evidence that lowering total and low-density lipoprotein cholesterol levels independently will reduce the incidence of coronary heart disease significantly.^3-5

Dr Stare correctly notes that dietary cholesterol plays a lesser role in the development of hypercholesterolemia than does the excessive intake of saturated fat and that smoking, obesity, diabetes, and a sedentary life-style also are significant risk factors for coronary heart disease. Had he spoken . . . [Full Text PDF of this Article]

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