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Thomas J. Bassler, MD
Palos Verdes Peninsula, Calif

JAMA. 1989;261(4):555.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Manninen et al¹ prove again that lowering the non-high-density lipoprotein cholesterol level lowers the risk of coronary disease.

What is missing is evidence that they have also lowered all-cause mortality. Since the treated subjects in this study experienced only two fewer fatal heart attacks, it would take only two noncoronary deaths to invalidate their conclusion that gemfibrozil was "effective in the primary prevention of CHD." . . . [Full Text PDF of this Article]

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