 |
|
Meta-analysis of Empirical Long-term Antiarrhythmic Therapy After Myocardial Infarction
Louis K. Hine, MD;
Nan M. Laird, PhD;
Peg Hewitt, MS;
Thomas C. Chalmers, MD
JAMA. 1989;262(21):3037-3040.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
SUDDEN cardiac death remains a major cause of mortality and a significant public health concern. At least 40% of sudden deaths occur in people with clinically overt heart disease, and among patients with coronary heart disease, the risk of sudden death is relatively greater for those patients who have had a myocardial infarction (MI) than for those who have not.1 Approximately 50% of MI-related deaths are sudden and usually caused by ventricular arrhythmias.2,3 Although the majority of these deaths occur in the earliest phases of MI,4 the risk of mortality beyond 1 year after MI remains four to eight times greater than that for comparable patients who did not have an MI.5,6 Approximately 35% to 40% of deaths that occur late after MI will be caused by sudden death.7
The presence of premature ventricular contractions (PVCs) after MI has been shown to be a risk
. . . [Full Text PDF of this Article]
Author Affiliations
From the Departments of Health Policy and Management (Drs Hine and Chalmers and Ms Hewitt) and Biostatistics (Dr Laird), Harvard School of Public Health, Boston, Mass; the Boston (Mass) Veterans Administration Medical Center (Dr Chalmers); and Mount Sinai School of Medicine, New York, NY (Dr Chalmers).
Footnotes
Published as an abstract in Clinical Research (1986;34:821A).
Reprint requests to the Technology Assessment Group, Harvard School of Public Health, 677 Huntington Ave, Room LL-7A, Boston, MA 02115 (Dr Chalmers).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
