This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Pamela Grim, MD; Peter Singer, MD; Mark Siegler, MD
Chicago, Ill

JAMA. 1989;262(22):3129.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply. —

We thank Dr Leith for his interest in our article on informed consent in emergency research. Our article addressed a single question: Can the conscious patient in the midst of a medical emergency provide adequate informed consent for a clinical research protocol? The article reviewed current federal guidelines for informed consent in this setting. It constructed a taxonomy of methods of obtaining informed consent in emergency research. Using as an example the case of thrombolytic therapy for myocardial infarction, we also described a novel two-step approach to obtaining informed consent.

Our article, then, was not intended as a clinical trial, but as an effort to establish a conceptual framework for the study of informed consent in emergency research. As Feinstein¹ has pointed out, the first question in designing clinical research is, "What is the question?" We stated in the article, "studies examining competency, risk aversiveness, and . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?