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Neil M. Resnick, MD; Susan L. Greenspan, MD
Brigham and Women's Hospital Boston, Mass

JAMA. 1989;262(24):3406-3407.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

We enjoyed the recent JAMA article on exercise,¹ but feel that the evidence supporting its preventive role in postmenopausal osteoporosis is less convincing than implied. Since the conclusions seem to be influenced by one study in particular,^2,3 it might be useful to examine it in more detail. Although the methods section is unclear, the study cited does not appear to be a randomized study of exercise⁴; patients seemed to volunteer to exercise and then were randomized to receive medication or a placebo, making selection bias likely. The bias may well have continued, because results were provided only for those 62% of subjects able to participate for 3 years. Moreover, the exercises included arm lifts and pulling wheelchairs, with the only reported end point being densitometric measurements of the forearm. No evidence was provided or can be inferred regarding the effect of such exercise on . . . [Full Text PDF of this Article]

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