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  Vol. 262 No. 24, December 22, 1989 TABLE OF CONTENTS
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Clinical and Biological Differences Between Recurrent Herpes Simplex Virus and Varicella-Zoster Virus Infections

Stephen E. Straus, MD

JAMA. 1989;262(24):3455-3458.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SELECTED CASES

CASE 1.—

An otherwise healthy 34year-old woman presented to the National Institutes of Health Clinical Center, Bethesda, Md, for evaluation and management of recurrent genital herpes. Her infection had been acquired a year earlier as a result of a sexual relationship with a partner who denied herpetic infection. The patient was able to recall vividly the details of the initial herpetic episode because of its considerable physical and emotional impact. Numerous painful ulcerative lesions had appeared over the labia and perineum. Urinary retention required hospitalization and catheterization for 2 days. Cultures of the lesions showed herpes simplex virus type 2. Intravenous acyclovir sodium, 5 mg/kg, was administered three times daily for 3 days followed by 7 days of treatment at home consisting of 200-mg capsules five times a day.

Infection recurred shortly after the patient completed treatment and about monthly thereafter. Mild tingling preceded each appearance of the . . . [Full Text PDF of this Article]


Author Affiliations

From the Medical Virology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, Bethesda, Md.


Footnotes

Reprint requests to National Institute of Allergy and Infectious Diseases, Bldg 10, Room 11N113, Bethesda, MD 20892 (Dr Straus).



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