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Gerald L. Klerman, MD; Myrna M. Weissman, PhD
The New York (NY) Hospital Cornell Medical Center

JAMA. 1989;262(7):900.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.—

The seasonal disorder hypothesis discussed by Dr Mueller is an interesting one and one we did not consider, partly because the Epidemiologic Catchment Area with the five-site data did not show an effect of season on rates of major depression.

Since the article was published, we have identified other population studies, using the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, or Research Diagnostic Criteria, undertaken in China, Taiwan, and Texas, thus giving us a broader range of latitudes to explore. The reason why a seasonal disorder would be increasing is unclear.

Our article entitled "Increasing Rate of Depression" does end with a large question. We think that the evidence for secular change in the rate of depression, based on thousands of persons from different countries and different investigations, is not entirely an artifact and that the absence of secular change in some parts of the world . . . [Full Text PDF of this Article]

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