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Council on Scientific Affairs and Council on Ethical and Judicial Affairs

JAMA. 1990;263(20):2790-2793.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CONFLICT of interest in clinical research defies simple definition: one researcher's conflict of interest may be another's mutually beneficial working relationship.¹ Conflict of interest must be clearly distinguished from scientific misconduct. The generally recognized patterns that constitute misconduct in science include plagiarism, deception, falsification, and/or fabrication of scientific data. Scientific misconduct compromises the integrity of the biomedical research process.

On the other hand, conflict of interest involves a distinct subset of issues. Conflict of interest is defined by Webster's Third New International Dictionary as "a conflict between the private interests and official responsibilities of a person in a position of trust." Although conflicts of interest may arise in any research relationship, they are most likely to occur when a researcher enters into a financial arrangement with a profit-making corporation. In that situation, the researcher's dedication to the advancement of medical knowledge may collide with the researcher's desire to increase . . . [Full Text PDF of this Article]

Author Affiliations
From the Council on Scientific Affairs and the Council on Ethical and Judicial Affairs, American Medical Association, Chicago, III.

Footnotes
This report was approved by the House of Delegates of the American Medical Association in December 1989 as a policy report of the Council on Scientific Affairs and the Council on Ethical and Judicial Affairs.

This report is not intended to be construed or to serve as a standard of medical care. Standards of medical care are determined on the basis of all of the facts and circumstances involved in an individual case and are subject to change as scientific knowledge and technology advance and patterns of practice evolve. This report reflects the views of scientific literature as of November 1989.

Reprint requests to the Council on Scientific Affairs, American Medical Association, 535 N Dearborn St, Chicago, IL 60610 (William R. Hendee, PhD).

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