
Coronary Perfusion Pressure in CPR-Reply
Norman Paradis, MD
Henry Ford Hospital Detroit, Mich
JAMA. 1990;263(24):3257-3258.
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In Reply.—
Dr McNeill seems to have misunderstood a number of important aspects of our study. We did not recommend measurement of the aortic-to— right atrial gradient (Ao-RA) in cardiac arrest patients simply as a means to predict outcome, but as a guide to therapy and a standard for future research. We emphasized that measurement of this gradient may allow optimization of standard therapies and "provide a rational basis for use of" alternative, potentially more effective techniques.
The study was undertaken in a basic emergency medical services system specifically because of the minimal differential risk in these patients.1 The absence of long-term survivors was expected in light of the study population. That "our sample does not represent the typical population of patients with cardiac arrest" is explicitly stated, as is a warning against applying these results to patients with short arrest times. Since the ramifications of these factors are
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