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Noori S. Dawood Al-Waili, MD
Baghdad, Iraq

JAMA. 1990;263(24):3258.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Nifedipine, a calcium channel blocking agent, relaxes smooth muscle and has been widely used for the treatment of coronary insufficiency and hypertension. Used for its spasmolytic effect, nifedipine has been found to be effective in relieving acute and recurrent urinary colic.¹ It exhibits relaxant activity in the intestinal tract and diminishes abnormal colonic motor response to distension in patients with irritable bowel syndrome.^2,3I, therefore, decided to conduct a double-blind, placebo-controlled study to test the benefit of oral nifedipine in acute intestinal colic.

Study.—

I studied 28 patients (18 men and 10 women) with acute intestinal colic due to bacillary or amebic dysentery. Their ages ranged from 20 to 35 years. The patients were seen within 12 hours of the start of their symptoms and had taken no medications. They underwent complete physical examination, and the diagnosis of the cause of their colic . . . [Full Text PDF of this Article]

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